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Particulate matter 2.5 triggers airway inflammation and bronchial hyperresponsiveness in mice by activating

Frontiers of Medicine 2021, Volume 15, Issue 5,   Pages 750-766 doi: 10.1007/s11684-021-0839-4

Abstract: Exposure to particulate matter 2.5 (PM2.5) potentially triggers airway inflammation by activating nuclearHowever, the function and specific mechanisms of SIRT2 in PM2.5-induced airway inflammation are largelyThe activation of p65 triggered airway inflammation, increment of mucus secretion by goblet cells, andMeanwhile, p65 phosphorylation and acetylation, airway inflammation, and bronchial hyperresponsivenessTriptolide (a specific p65 inhibitor) reversed p65 activation and ameliorated PM2.5-induced airway inflammation

Keywords： particulate matter 2.5     sirtuin 2     p65     airway inflammation     bronchial hyperresponsiveness     triptolide    

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Tim-3 mRNA expression in peripheral blood lymphocytes from asthmatic patients

Xiaoxia LU, Weikun HU, Shengdao XIONG, Guopeng XU, Fen LAN

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 187-190 doi: 10.1007/s11684-009-0033-6

Abstract: forced vital capacity) to explore the role of Tim-3 in the development and progression of asthmatic inflammationmRNA in peripheral blood lymphocytes might be involved in the development and progression of asthmatic inflammation

Keywords： asthma     airway inflammation     peripheral blood lymphocyte     Tim-3    

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Insult of gastroesophageal reflux on airway: clinical significance of pharyngeal nozzle

Zhonggao Wang,Zhiwei Hu,Jimin Wu,Feng Ji,Hongtao Wang,Yungang Lai,Xiang Gao,Yachan Ning,Chengchao Zhang,Zhitong Li,Weitao Liang,Jianjun Liu

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 117-122 doi: 10.1007/s11684-014-0343-1

Abstract: time of global paying the highest attention to the worst insults of smoking as well as haze on the airwaymany medical personnel, do not know how badly the gastroesophageal reflux (GER) insults on our own airwayas a nozzle, so as to produce numerous micro-particles and reach the oro-nasal cavity and also the airwayThe GER induced airway challenge is a treatable and preventive entity, as soon as a diagnosis is made

Keywords： gastroesophageal reflux     airway     pharyngeal nozzle     micro-aspiration     asthma    

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Cytokines and inflammation in adipogenesis: an updated review

Ning Jiang, Yao Li, Ting Shu, Jing Wang

Frontiers of Medicine 2019, Volume 13, Issue 3,   Pages 314-329 doi: 10.1007/s11684-018-0625-0

Abstract: Meanwhile, chronic low-grade inflammation is commonly observed in obese populations.

Keywords： cytokines     inflammation     adipogenesis     type 2 diabetes mellitus     metabolic disorder    

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Appendiceal inflammation affects the length of stay following appendicectomy amongst children: a myth

Khurram Siddique, Shirin Mirza, Gandra Harinath

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 264-269 doi: 10.1007/s11684-013-0259-1

Abstract:

The effect of the severity of appendiceal inflammation on post-operative stay in children followingThis study was conducted to determine the association between the severity of appendiceal inflammationThe association of the severity of appendiceal inflammation and post-operative stay was assessed by multivariableMacroscopically perforated appendix, histological inflammation and post-operative complications wereperforated appendix or post-operative complications while it remained unaffected by the histological inflammation

Keywords： appendiceal inflammation     post-operative stay     paediatrics    

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for preventing peritoneal fibrosis in peritoneal dialysis patients: new insights based on peritoneal inflammation

Zhen Zhang, Na Jiang, Zhaohui Ni

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 349-358 doi: 10.1007/s11684-017-0571-2

Abstract: Inflammation and angiogenesis are key events during the pathogenesis of peritoneal fibrosis.peritoneal fibrosis and recent research progress on key fibrogenic molecular mechanisms in peritoneal inflammationFurthermore, novel strategies targeting peritoneal inflammation and angiogenesis to preserve the PM are

Keywords： peritoneal dialysis     peritoneal fibrosis     inflammation     angiogenesis    

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Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation

Weijian Hang, Chen Chen, Xin A. Zhang, Dao Wen Wang

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 638-643 doi: 10.1007/s11684-021-0831-z

Abstract: of overwhelming inflammatory responses in the pathogenesis of COVID-19 and the effectiveness of anti-inflammation

Keywords： COVID-19     endothelial dysfunction     inflammation reaction     cytokine storm    

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Expression of renal cubilin and its potential role in tubulointerstitial inflammation induced by albumin

YANG Jurong, HE Yani, SHEN Haiying, DING Hanlu, LI Kailong, WANG Huiming

Frontiers of Medicine 2008, Volume 2, Issue 1,   Pages 25-34 doi: 10.1007/s11684-008-0006-1

Abstract: Over-reabsorption of filtered proteins, notably albumin, has been proved to trigger interstitial inflammationalbumin-induced production of MCP-1 and RANTES by renal tubular cells, which further initiated tubulointerstitial inflammation
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Inflammation and liver tumorigenesis

Beicheng Sun, Michael Karin

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 242-254 doi: 10.1007/s11684-013-0256-4

Abstract:

Inflammation has been considered as one of the hallmarks of cancer, and chronic hepatitis is a majorThis review will focus on the pathogenic role of inflammation in hepatocarcinogenesis and will discuss

Keywords： hepatocellular carcinoma     hepatitis     cytokine     stem cell     miRNA    

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Discovery and repurposing of artemisinin

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 1-9 doi: 10.1007/s11684-021-0898-6

Abstract: We will then discuss how artemisinin and its derivatives could be repurposed to treat cancer, inflammation

Keywords： artemisinin     drug repurposing     cancer     inflammation     COVID-19     traditional Chinese medicine    

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Plasma transthyretin is a nutritional biomarker in human morbidities

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 540-550 doi: 10.1007/s11684-022-0940-3

Abstract: Taken together, the data indicate that malnutrition and inflammation may similarly suppress the production

Keywords： lean body mass     nutritional status     transthyretin     malnutrition     inflammation     amyloidosis    

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Mechanisms of insulin resistance in obesity

Jianping Ye

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 14-24 doi: 10.1007/s11684-013-0262-6

Abstract: In those hypotheses, inflammation, mitochondrial dysfunction, hyperinsulinemia and lipotoxicity have

Keywords： type 2 diabetes     energy expenditure     inflammation     lipotoxicity     mitochondria     hyperinsulinemia     adenosine    

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Role of Akkermansia muciniphila in the development of nonalcoholic fatty liver disease: current knowledge and perspectives

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 667-685 doi: 10.1007/s11684-022-0960-z

Abstract: The recovery of A. muciniphila presented benefits in preventing hepatic fat accumulation and inflammationThe modulation mechanisms by which A. muciniphila acts to improve hepatic inflammation are mainly

Keywords： Akkermansia muciniphila     NAFLD     NASH     steatosis     inflammation    

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Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes

Jianping Ye

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 139-145 doi: 10.1007/s11684-015-0377-z

Abstract:

In obesity, chronic inflammation is believed to induce insulin resistance and impairs adipose tissue

Keywords： inflammation     obesity     cytokine     energy expenditure     insulin resistance    

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Hyperosmolarity promotes macrophage pyroptosis by driving the glycolytic reprogramming of corneal epithelial cells in dry eye disease

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 781-795 doi: 10.1007/s11684-023-0986-x

Abstract: development of dry eye disease (DED) by mediating the disruption of ocular surface homeostasis and triggering inflammationto greatly induce HCECs’ metabolic reprogramming, which may be the primary cause of the subsequent inflammationsuggested that hyperosmolar-induced glycolytic reprogramming played an active role in promoting DED inflammation

Keywords： dry eye disease     glycolytic reprogramming     pyroptosis     inflammation     2-DG    

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Title Author Date Type Operation

Particulate matter 2.5 triggers airway inflammation and bronchial hyperresponsiveness in mice by activating

Journal Article

Tim-3 mRNA expression in peripheral blood lymphocytes from asthmatic patients

Xiaoxia LU, Weikun HU, Shengdao XIONG, Guopeng XU, Fen LAN

Journal Article

Insult of gastroesophageal reflux on airway: clinical significance of pharyngeal nozzle

Zhonggao Wang,Zhiwei Hu,Jimin Wu,Feng Ji,Hongtao Wang,Yungang Lai,Xiang Gao,Yachan Ning,Chengchao Zhang,Zhitong Li,Weitao Liang,Jianjun Liu

Journal Article

Cytokines and inflammation in adipogenesis: an updated review

Ning Jiang, Yao Li, Ting Shu, Jing Wang

Journal Article

Appendiceal inflammation affects the length of stay following appendicectomy amongst children: a myth

Khurram Siddique, Shirin Mirza, Gandra Harinath

Journal Article

for preventing peritoneal fibrosis in peritoneal dialysis patients: new insights based on peritoneal inflammation

Zhen Zhang, Na Jiang, Zhaohui Ni

Journal Article

Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation

Weijian Hang, Chen Chen, Xin A. Zhang, Dao Wen Wang

Journal Article

Expression of renal cubilin and its potential role in tubulointerstitial inflammation induced by albumin

YANG Jurong, HE Yani, SHEN Haiying, DING Hanlu, LI Kailong, WANG Huiming

Journal Article

Inflammation and liver tumorigenesis

Beicheng Sun, Michael Karin

Journal Article

Discovery and repurposing of artemisinin

Journal Article

Plasma transthyretin is a nutritional biomarker in human morbidities

Journal Article

Mechanisms of insulin resistance in obesity

Jianping Ye

Journal Article

Role of Akkermansia muciniphila in the development of nonalcoholic fatty liver disease: current knowledge and perspectives

Journal Article

Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes

Jianping Ye

Journal Article

Hyperosmolarity promotes macrophage pyroptosis by driving the glycolytic reprogramming of corneal epithelial cells in dry eye disease

Journal Article